- 淇濆湥闆诲瓙榧籧Nose 鍦ㄦ灉閰掗ⅷ(f膿ng)鍛冲垎鏋愪腑鐨勬噳(y墨ng)鐢ㄧ爺绌�
- 鐧�(f膩)甯冩棩鏈燂細2025-03-21 鐎忚娆℃暩(sh霉)锛�176
涓�銆佺爺绌惰儗鏅�
鏋滈厭甯傚牬杩戝勾渚嗙櫦(f膩)灞曡繀閫�锛屽叾鐛ㄧ壒棰�(f膿ng)鍛虫槸鍚稿紩娑堣不鑰呯殑闂�(gu膩n)閸靛洜绱犱箣涓�銆傛灉閰掗ⅷ(f膿ng)鍛冲彈鍘熸枡銆佺櫦(f膩)閰靛伐钘濄�佸劜瀛樻浠剁瓑澶氱ó鍥犵礌褰遍熆锛屾垚鍒嗗京(f霉)闆溿�傚偝绲�(t菕ng)鐨勬灉閰掗ⅷ(f膿ng)鍛冲垎鏋愭柟娉�锛屽鎰熷畼瑭曞児渚濊炒浜哄伐涓昏鍒ゆ柗锛屽瓨鍦ㄥ�嬮珨宸暟澶�銆佹晥鐜囦綆绛夊晱椤�锛涘寲瀛�(xu茅)鍒嗘瀽鏂规硶闆栬兘绮剧⒑妾㈡脯鎴愬垎锛屼絾鎿嶄綔绻佺懀銆佹垚鏈珮銆傞浕瀛愰蓟浣滅偤涓�绋柊鍨嬫娓妧琛�(sh霉)锛屽叿鏈夊揩閫�銆佸瑙�銆侀噸寰�(f霉)鎬уソ绛夊劒(y艒u)榛�锛岃兘褰岃鍌崇当(t菕ng)鏂规硶鐨勪笉瓒�锛屽湪鏋滈厭棰�(f膿ng)鍛冲垎鏋愰牁(l菒ng)鍩熷睍鐝�(xi脿n)鍑哄法澶ф經鍔�锛屽皪鎻愬崌鏋滈厭鍝佽唱(zh矛)銆佸劒(y艒u)鍖栫敓鐢�(ch菐n)宸ヨ棟鍏锋湁閲嶈鎰忕京銆�
浜�銆佸椹楁柟娉�
2.1 瀵﹂鏉愭枡
閬稿彇鏂囨獢涓彁鍙婄殑8绋灉閰�锛屽寘鎷�5绋憽钀勯厭锛堟柊鐤嗗崐骞�SJ銆佹硶鍦嬪崐鐢�LS銆佹渤鍖楀共HY銆佽タ鐝墮骞�TJ銆佹硶鍦嬪共FT锛�銆�1绋櫦(f膩)閰甸潚姊呴厭FZ銆�1绋棈(l谩n)鑾撻厭HZ浠ュ強1绋厤鍒堕潚姊呴厭LM銆傞�欎簺鏋滈厭娑佃搵浜嗕笉鍚屽師鏂欏拰鐢�(ch菐n)鍦�锛屽叿鏈変唬琛ㄦ�с��
2.2 闆诲瓙榧�cNose妾㈡脯
閲囩敤Super Nose闆诲瓙榧荤郴绲�(t菕ng)锛岃┎绯荤当(t菕ng)閰嶅倷14绋偝鎰熷櫒锛屽彲妾㈡脯纭寲姘�銆佺～鍖栫墿銆侀唶椤�銆侀叜椤�銆侀啗椤炲拰鑺抽鍖栧悎鐗╃瓑澶氱ó棣欐埃鎴愬垎銆傚椹楁檪锛屽彇10mL绋�閲嬪崄鍊嶇殑鏋滈厭妯ｅ搧缃簬50mL鐜荤拑灏忕摱涓�锛屽钩琛�60min浠ュ舰鎴愰爞绌�銆傞浕瀛愰蓟绯荤当(t菕ng)闋�(y霉)鐔�60min鍚�锛岃ō(sh猫)缃偝鎰熷櫒娓呮礂鏅傞枔100s銆侀噰妯ｉ枔闅�120s銆侀��(j矛n)妯ｉ�熺巼1L/min閫�(j矛n)琛屾娓紝妾㈡脯绲�(ji茅)鏋滀互G/G90琛ㄧず锛屽嵆妯ｅ搧闆诲皫(d菐o)鐜囪垏娓呮綌绌烘埃闆诲皫(d菐o)鐜囦箣姣斻��
2.3 鏁�(sh霉)鎿�(j霉)铏曠悊
閬嬬敤涓绘垚鍒嗗垎鏋愶紙PCA锛夊拰鍋忔渶灏忎簩涔樻硶鍒ゅ垾鍒嗘瀽锛�PLS-DA锛夊皪闆诲瓙榧�cNose妾㈡脯鏁�(sh霉)鎿�(j霉)閫�(j矛n)琛岃檿鐞�銆�PCA鐢ㄤ簬闄嶄綆鏁�(sh霉)鎿�(j霉)缍害锛屽彲瑕栧寲涓嶅悓鏋滈厭妯ｅ搧闁撶殑宸暟锛�PLS-DA閫氶亷寤虹珛鍒ゅ垾妯″瀷锛岄��(j矛n)涓�姝ュ崁(q奴)鍒嗕笉鍚岄鍨嬬殑鏋滈厭锛岃⿻浼版ā鍨嬬殑闋�(y霉)娓兘鍔涘拰鍙潬鎬�銆�
涓�銆佸椹楃祼(ji茅)鏋�
3.1 鍌虫劅鍣ㄩ熆鎳�(y墨ng)宸暟
闆烽仈(d谩)鍦栭’绀猴紝鍌虫劅鍣�S7-S13灏嶆墍鏈夋ǎ鍝佺殑闊挎噳(y墨ng)姘村钩鐩歌繎锛�>0.01锛�锛岃�屽叾浠栧偝鎰熷櫒闊挎噳(y墨ng)宸暟椤憲锛�p<0.01锛夈�備緥濡�锛屾ǎ鍝�SJ鐨勯儴鍒嗗偝鎰熷櫒闊挎噳(y墨ng)杓冧綆锛�FT鍓囪純楂�銆傞�欒〃鏄庝笉鍚屾灉閰掍腑鎻櫦(f膩)鎬у寲鍚堢墿婵冨害涓嶅悓锛屽奖闊夸簡鍌虫劅鍣ㄩ熆鎳�(y墨ng)锛岄珨鐝�(xi脿n)鍑洪浕瀛愰蓟灏嶄笉鍚屾灉閰掗ⅷ(f膿ng)鍛崇殑鏁忔劅鎬�銆�
3.2 鏋滈厭鍗�(q奴)鍒嗚兘鍔�
PCA鍒嗘瀽绲�(ji茅)鏋滆〃鏄�锛岄浕瀛愰蓟鏁�(sh霉)鎿�(j霉)鐨勪富鎴愬垎鍒嗘瀽鑳借В閲嬬附鏂瑰樊鐨�92.1%锛�t[1]=80.2%锛�t[2]=11.9%锛�R²X(cum)=92.1%锛�Q²(cum)=27.3%锛�锛岃鏄庨浕瀛愰蓟鑳芥湁鏁堝崁(q奴)鍒嗕笉鍚屾灉閰掋��PLS-DA妯″瀷椤ず鍑烘洿寮风殑鑱氶鏁堟灉锛�R²X=0.994锛�R²Y=0.207锛�Q²=0.236锛�锛屼笖缍�(j墨ng)閬�200娆＄疆鎻涙椹�锛屾ā鍨嬪彲闈狅紙R²=0.0046锛�Q²=-0.079锛�銆傞�欐剰鍛宠憲闆诲瓙榧荤祼(ji茅)鍚�PLS-DA妯″瀷鍙簴(zh菙n)纰哄崁(q奴)鍒嗕笉鍚岄鍨嬫灉閰�銆�
3.3 鑸囧叾浠栧垎鏋愭柟娉曠殑涓�鑷存��
闆诲瓙榧绘娓祼(ji茅)鏋滆垏GC-TOF/MS銆�GC-IMS绛夊垎鏋愭柟娉曠殑绲�(ji茅)鏋滃叿鏈変竴鑷存�с�傛彯鐧�(f膩)鎬у寲鍚堢墿鐨勭祫鎴愬拰鍚噺宸暟鏈冨悓鏅傚奖闊块浕瀛愰蓟鍌虫劅鍣ㄩ熆鎳�(y墨ng)鍜岃壊璀滃垎鏋愮祼(ji茅)鏋�锛岄��(j矛n)涓�姝ヨ瓑鏄庨浕瀛愰蓟鍦ㄦ灉閰掗ⅷ(f膿ng)鍛冲垎鏋愪腑鐨勬湁鏁堟��銆�
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- 涓婁竴绡囷細涓婃捣淇濆湥闆诲瓙榧籧Nose锛氭灣娈煎搧璩�(zh矛)棰�(f膿ng)鍛崇爺绌剁殑闂�(gu膩n)閸靛姪鍔�
- 涓嬩竴绡囷細淇濆湥闆诲瓙鑸宑Tongue鍦ㄩ鍛宠偨鍛抽亾鐗瑰緛鍒嗘瀽涓殑鎳�(y墨ng)鐢�
琛屾キ(y猫)璩囪▕鎵�鍦ㄤ綅缃細棣栭爜 >> 琛屾キ(y猫)璩囪▕ >> 淇濆湥闆诲瓙榧籧Nose 鍦ㄦ灉閰掗ⅷ(f膿ng)鍛冲垎鏋愪腑鐨勬噳(y墨ng)鐢ㄧ爺绌�
